Viking Therapeutics is experiencing significant positive momentum this October, driven by substantial progress in its obesity treatment candidate VK2735. The biotechnology firm’s shares have benefited from multiple favorable clinical developments and a robust financial position of $715 million. A newly initiated maintenance dosing study presents a particularly promising competitive advantage in the weight management pharmaceutical sector.
Strategic Positioning Through Flexible Dosing Options
The company’s VK2735 positions itself as a direct competitor to Tirzepatid while offering distinct differentiation through adaptable administration methods. The maintenance dose investigation specifically targets a fundamental limitation of current obesity treatments—sustaining weight reduction following initial therapy.
On October 21, Viking launched a groundbreaking Phase 1 trial examining maintenance protocols for VK2735. This randomized, double-blind study involves 180 obese adults who will receive weekly injections for 19 weeks before transitioning to various maintenance regimens:
• Monthly subcutaneous administration
• Daily oral dosage
• Weekly oral medication
• Placebo control group
This comprehensive approach to long-term treatment adherence could substantially differentiate Viking’s offering within the competitive landscape.
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Upcoming Scientific Presentations Showcase Progress
The scientific community will receive multiple updates on Viking’s development program through several high-profile conferences. During ObesityWeek 2025 in Atlanta (November 4-7), the company will present two poster displays—one detailing Phase 2 VENTURE trial outcomes and another outlining the design of the ongoing Phase 3 VANQUISH-1 investigation. Additional findings will be shared at the American Heart Association Scientific Sessions 2025 in New Orleans.
Advanced Clinical Program Advances Toward Approval
Viking’s pivotal Phase 3 studies continue to progress according to schedule. The VANQUISH-1 trial is enrolling 4,500 obese adults without diabetes, while VANQUISH-2 focuses on 1,100 adults with Type 2 diabetes. Both investigations span 78 weeks and could potentially support regulatory approval applications.
Financial Strength Supports Ambitious Development Timeline
Third-quarter financial statements reveal substantial liquidity with $715 million in reserves—adequate funding to complete the planned Phase 3 trials. Research expenditures increased to $90 million for the quarter, compared to $22.8 million during the same period last year, reflecting the accelerated pace of clinical development.
The maintenance dosing study represents a strategic initiative to address a critical challenge in obesity management and could establish Viking’s competitive edge in the rapidly expanding metabolic treatment market.
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