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Mirum Pharmaceuticals Shares Poised for Breakout Ahead of Earnings Report

Felix Baarz by Felix Baarz
November 2, 2025
in Analysis, Earnings, Pharma & Biotech
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Investors are closely watching Mirum Pharmaceuticals as the biopharmaceutical company prepares to release its third-quarter 2025 financial results this Tuesday. The upcoming earnings announcement has generated significant market anticipation, with analysts projecting substantial growth for the rare disease specialist.

Unprecedented Revenue Growth Projected

Market researchers are forecasting a remarkable 43.9% year-over-year revenue surge for Mirum’s third quarter, with expectations centered around $130 million. This substantial projected increase signals robust commercial performance for the company’s approved therapies and demonstrates impressive expansion momentum for an organization focused on rare disease treatments.

The Path Toward Financial Sustainability

Despite the optimistic revenue projections, Mirum’s journey to profitability continues. Financial experts anticipate the company will report a loss of $0.16 per share for the July-September period. This scenario is characteristic of biotechnology firms navigating the delicate balance between growth investments and achieving financial breakeven.

Should investors sell immediately? Or is it worth buying Mirum Pharmaceuticals?

Overwhelming Analyst Confidence

The investment community maintains a decidedly bullish stance on Mirum’s prospects. Eleven financial analysts have issued “Strong Buy” or “Buy” recommendations for the company’s shares. Their collective assessment points to significant upside potential, with a median price target of $81.50 representing a 11.4% increase from the recent closing price of $72.20.

Advancing Clinical Development Programs

Beyond the immediate focus on quarterly performance, Mirum continues to advance multiple promising research initiatives:

  • MRM-3379 for Fragile X Syndrome: The Phase 2 clinical trial launched in early October, marking a crucial advancement in neurocognitive disorder research
  • Volixibat Studies: Patient enrollment has concluded for the VISTAS study in primary sclerosing cholangitis (PSC), with key results anticipated in the second quarter of 2026
  • LIVMARLI Expansion: The Phase 3 EXPAND study is scheduled to complete recruitment in 2026, potentially broadening the treatment’s therapeutic applications

As Tuesday’s earnings announcement approaches, market participants are questioning whether Mirum can deliver results that match the elevated expectations. A strong performance could potentially accelerate the stock’s upward trajectory and establish new valuation benchmarks for the emerging biopharmaceutical company.

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Tags: Mirum Pharmaceuticals
Felix Baarz

Felix Baarz

My name is Felix Baarz, and I look back on over fifteen years of experience as a business journalist. I have always been fascinated by the mechanisms and dynamics of global financial markets as well as the complex economic and political interconnections that shape our world. With this passion, I have made a name for myself as an expert on international financial markets and dedicate myself with great commitment to making even the most complex topics understandable and accessible to my readers. My roots lie in Cologne, where I was born and raised. Early on, my curiosity about economic topics and international developments sparked my interest in journalism. After completing my studies, I began my career as a business editor at a respected German trade publication. Here I laid the foundation for my professional career, but my curiosity soon drew me out into the wider world. A turning point in my life was moving to New York, where I lived for six years and gained insight into leading media houses. In this vibrant metropolis, I was able to report firsthand from the heart of the global financial world. From daily developments on Wall Street to major economic policy decisions that make waves worldwide, I had the opportunity to write about central topics that move people and markets alike. This time shaped my perspective and sharpened my view of global interconnections.

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