Jasper Therapeutics has announced that they will be presenting groundbreaking preclinical data on the effectiveness of Briquilimab, an anti-CD117 antibody, in preventing a wide range of allergic reactions in mice. The study specifically targets mice that express chimeric human and mouse CD117, and the results are highly promising.
The presentations will take place at the American Academy of Allergy, Asthma, and Immunology (AAAAI) Annual Meeting on February 23-25, 2024. The details of each presentation are as follows:
1. Abstract Title: Briquilimab, An Anti-CD117 Antibody, Prevents Passive Systemic Anaphylaxis in Mice Expressing Chimeric Human and Mouse CD117 Through Mast Cell Depletion.
– Poster Number: 024
– Session Title: Therapeutic Trials in Allergic Skin Disorders and Anaphylaxis 2024
– Session Type: Poster Session
– Session Date / Time: Friday, February 23, 2024; 3:15 p.m. – 4:15 p.m. EST
2. Abstract Title: Briquilimab, an Anti-CD117 Antibody, Prevents Cockroach Allergen Induced Allergic Asthma in Mice Expressing Chimeric Human and Mouse CD117.
– Publication Number: 441
– Session Title: Old Therapeutics and New Targets in Asthma
– Session Type: Oral Abstract Session
– Session Date / Time: Saturday, February 24, 2024; 2:00 p.m. – 3:15 p.m. EST
3. Abstract Title: Amelioration Of Mrgprb2-Mediated Anaphylactoid Drug Reactions With Briquilimab, An Anti-CD117 Antibody, Through Mast Cell Depletion In Mice Expressing Chimeric Human And Mouse CD117.
– Poster Number: 747
– Session Title: Around the Horn: Dermatology, Drug Allergy, Anaphylaxis, Insect Hypersensitivity
– Session Type: Featured Poster Session
– Session Date / Time: Sunday, February 25, 2024; 4:45 p.m. – 6:15 p.m. EST
These presentations highlight the potential of Briquilimab in preventing various allergic reactions in mice, specifically targeting chimeric human and mouse CD117. The research conducted by Jasper Therapeutics may have significant implications for the development of therapeutics for allergic conditions in humans. Stay tuned for the groundbreaking findings from this study.
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